Integrating Evolutionary and Engineering Approaches to Failure Analyses

Integrating Evolutionary and Engineering Approaches to Failure Analyses

(UTC-05:00) Eastern Time (US & Canada)
  • Barbara Natterson-Horowitz
    Harvard Medical School

    Barbara Natterson-Horowitz is a cardiologist and evolutionary biologist on the faculty of Harvard Medical School, Harvard University’s Department of Human Evolutionary Biology, and the David Geffen School of Medicine at UCLA, where she is also founding codirector of the university’s Evolutionary Medicine Program. Her phylogeny lab ...

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  • Steven A. Frank
    University of California, Irvine

    Steven A. Frank is Donald Bren Professor and UCI Distinguished Professor in the School of Biological Sciences at the University of California, Irvine. He studies the natural processes that have shaped the history and the function of organisms. Through the study of biological history and associated genetic changes, he has contributed to ...

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  • Denis A. Cortese
    Mayo Clinic (retired)

    Denis A. Cortese is a Foundation Professor at Arizona State University (ASU), director of the university’s Center for Healthcare Delivery and Policy, and president of the nonprofit Healthcare Transformation Institute based in Phoenix. He is a former president and CEO of the Mayo Clinic, and currently serves on the boards of directors for ...

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  • Norman R. Augustine
    Lockheed Martin Corp (retired)

    Norman R. Augustine has been chair and CEO of Lockheed Martin; president and then CEO of Lockheed Martin Corporation upon its formation in 1995; president, COO, CEO, and chair of Martin Marietta Corporation; and under (later, acting) secretary of the Army.

    He was chair of the Council of the National Academy of Engineering, president and ...

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  • James P. Collins
    Arizona State University

    James P. Collins is Virginia M. Ullman Professor of Natural History and the Environment at Arizona State University. His research group studies host-pathogen biology and its relationship to the decline of species, the intellectual history of ecology’s development as a science, ecological ethics, and adaptation to change in academic and ...

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Explaining system failures is the focus of enormous efforts in engineering. Explaining vulnerability to disease is the focus for parallel efforts in medicine and public health. Methods from engineering have potential important applications in medicine, and evolutionary explanations for vulnerability to disease may prove useful in engineering. This virtual colloquium of the Forum on Complex Unifiable Systems will engage engineers, clinicians, evolutionary biologists, and related scholars and practitioners, to develop the opportunities at this interface. Questions to be addressed include:

  1. How are failure modes in engineered and evolved systems similar and different?
  2. How can engineering approaches to failure analysis assist in understanding disease?
  3. How can evolutionary explanations of disease vulnerability advance the analysis of engineering failures?
  4. What characteristics make some systems intrinsically vulnerable to failure?
  5. What next steps can develop the synergies between evolutionary and engineering explanations approaches to system failures and expand them to social and financial systems?

Meeting Agenda

Please register here to join this forum on December 5-6, 2022.