Articles
  • [Periodical Article]

    The Convergence of Engineering and the Life Sciences

    Editors' Note Two entities converge when advances and time channel them to the same point. This is an appropriate way to characterize and address converging research in life sciences and engineering, computation, and physical sciences. The story of convergence starts in 1953 when molecular ... Read More

    Author: Phillip A. Sharp and Robert Langer

    Fall Issue of The Bridge on the Convergence of Engineering and the Life Sciences

    Release date: Fall 2013

    Volume: 43

    Number: 3

  • [Periodical Article]

    Nanotechnology An Enduring Bridge Between Engineering and Medicine

    Nanotechnology has matured over the past 20 years from a field focused on understanding miniaturization and its consequences to one defined by the rational design, synthesis, and manipulation of nanoscale objects. Many advances in nanotechnology have had an extraordinary impact specifically on the ... Read More

    Author: Sarah Hurst Petrosko, Catherine A. Fromen, Evelyn Auyeung, Joseph M. DeSimone, and Chad A. Mirkin

    Fall Issue of The Bridge on the Convergence of Engineering and the Life Sciences

    Release date: Fall 2013

    Volume: 43

    Number: 3

  • [Periodical Article]

    Understanding and Harnessing the Immune System for the Rational Design of Therapies and Vaccines

    The immune system provides protection from infectious pathogens, and its aberrant regulation is implicated in several diseases. Vaccination, one of the greatest triumphs of modern medicine, is evidence that the immune system can be harnessed and manipulated to improve the human condition. But ... Read More

    Author: Arup K. Chakraborty and Mark M. Davis

    Fall Issue of The Bridge on the Convergence of Engineering and the Life Sciences

    Release date: Fall 2013

    Volume: 43

    Number: 3

  • [Periodical Article]

    Systems Biology and Systems Pharmacology

    Definitions of systems biology are as broad ranging as the field itself. An early offering was from the Institute for Systems Biology: Systems biology does not investigate individual genes or proteins one at a time, as has been the highly successful mode of biology for the past 30 years. ... Read More

    Author: Douglas A. Lauffenburger and Kathleen M. Giacomini

    Fall Issue of The Bridge on the Convergence of Engineering and the Life Sciences

    Release date: Fall 2013

    Volume: 43

    Number: 3

  • [Periodical Article]

    Regenerative Engineering Materials, Mimicry, and Manipulations to Promote Cell and Tissue Growth

    Since time immemorial literature and art have depicted the desire to recreate or regenerate human life or to transplant parts from one individual to another. An early example is the Fra Angelico painting Healing of Justinian , which showed the transplantation in the third century AD of an ... Read More

    Author: Cato T. Laurencin, George Q. Daley, and Roshan James

    Fall Issue of The Bridge on the Convergence of Engineering and the Life Sciences

    Release date: Fall 2013

    Volume: 43

    Number: 3

  • [Periodical Article]

    Microfabrication The Interface Between Medicine and Engineering

    Over the past half-century the semiconductor industry developed a powerful set of manufacturing tools that enable highly parallel fabrication of electronic devices with an extraordinarily large number of integrated components. A key part of this process is the use of lithographic techniques to ... Read More

    Author: Stephen R. Quake

    Fall Issue of The Bridge on the Convergence of Engineering and the Life Sciences

    Release date: Fall 2013

    Volume: 43

    Number: 3

  • [Periodical Article]

    Applications of Synthetic Biology to Enhance Life

    For centuries a principal goal of science has been, first, to understand life at its most basic level and, second, to learn to control it. René Descartes (1596–1650), a pioneer of optics most often associated with “I think, therefore I am,” looked forward in his Discourse ... Read More

    Author: Jay D. Keasling and J. Craig Venter

    Fall Issue of The Bridge on the Convergence of Engineering and the Life Sciences

    Release date: Fall 2013

    Volume: 43

    Number: 3